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2015-12-14

Biotie Therapies Oyj: Disclosure under Chapter 9, Section 5 of the Finnish Securities Markets Act

BIOTIE THERAPIES CORP. STOCK EXCHANGE RELEASE December 14,
2015 at 3.10 p.m.

Disclosure under Chapter 9, Section 5 of the Finnish Securities Markets Act

Biotie Therapies Corp. (Nasdaq Helsinki BTH1V; NASDAQ: BITI) ("Biotie" or the
"Company") has on December 12, 2015 received a notification in accordance
with Chapter 9, Section 5 of the Finnish Securities Markets Act from Versant
Ventures V, LLC on behalf of itself and Versant Venture Capital V, L.P. as a
result of the implementation of changes to the transparency directive in the
Finnish Securities Market Act.

According to the notification, the total number of Biotie shares owned
directly or through financial instruments by Versant Ventures V, LLC and its
funds was 8.80 per cent of Biotie's total number of shares and voting rights
on 26 November 2015. Biotie's registered total number of shares and voting
rights amounting to 1,086,940,271 has been used in the calculation of
percentages for the announcement.

Total positions of Versant Ventures V, LLC and its funds subject to the
notification:

-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
| % of shares and voting rights (total of A) % of shares and voting rights through financial instruments Total of both in % (A + B) |
| (total of B) |
| Resulting situation on the date on which threshold was crossed 5.39 3.41 8.80 |
|or reached |
| Position of previous notification (if applicable) 5.97 N/A N/A |
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Notified details of the resulting situation on the date on which the threshold
was crossed or reached:

A: Shares and voting rights

---------------------------------------------------------------------------------------------
| Class/type of shares Number of shares and voting rights % of shares and voting rights |
| |
|ISIN code (if possible) |
| Direct Indirect Direct Indirect |
| |
| (SMA 9:5) (SMA 9:6 and 9:7) (SMA 9:5) (SMA 9:6 and 9:7) |
| Shares - 37,051,651 - 3.41 |
| |
|(FI0009011571) |
| Shares - 21,493,760 - 1.98 |
| |
|(FI0009011571) |
|represented by |
|268,672 ADSs |
| |
| SUBTOTAL A 58,545,411 5.39 |
---------------------------------------------------------------------------------------------
For further information on the ADSs representing the Company's shares, the
notification refers to the stock exchange release issued by the Company on
June 11, 2015.

B: Financial instruments according to SMA 9:6a

-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
| Type of financial instrument Expiration date Exercise/ Physical or cash settlement Number of shares and voting rights % of shares and voting rights |
| |
| Conversion period |
| Warrants entitling to shares (new or treasury shares) Nov 1, 2020 Nov 1, 2015 - Nov 1, 2020 Physical settlement 37,051,651 3.41 |
|(FI0009011571) |
| |
| SUBTOTAL B 37,051,651 3.41 |
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
For further information on the warrants, the notification refers to the stock
exchange release issued by the Company on April 23, 2015.

Full chain of controlled undertakings through which the voting rights and/or
the financial instruments are effectively held starting with the ultimate
controlling natural person or legal entity:

---------------------------------------------------------------------------------------------------------------------------------------------------------
| Name % of shares and voting rights % of shares and voting rights through financial instruments Total of both |
| Versant Ventures V, LLC 0 0 0 |
| Versant Venture Capital V, L.P. 4.73 2.99 7.72 |
| Versant Affiliates Fund V, L.P. 0.14 0.09 0.23 |
| Versant Ophthalmic Affiliates Fund I, L.P. 0.16 0.10 0.26 |
| Versant Ventures V GP-GP (Canada), Inc. 0 0 0 |
| Versant Ventures V (Canada), L.P. 0 0 0 |
| Versant Venture Capital V (Canada) LP 0.36 0.23 0.59 |
---------------------------------------------------------------------------------------------------------------------------------------------------------
According to the notification, Versant Ventures V, LLC is the sole general
partner of (i) Versant Venture Capital V, L.P., (ii) Versant Affiliates Fund
V, L.P. and (iii) Versant Ophthalmic Affiliates Fund I, L.P. and (iv) the
sole shareholder of Versant Ventures V GP-GP (Canada), Inc. Versant Ventures
V GP-GP (Canada), Inc. is the sole general partner of Versant Ventures V
(Canada), L.P., which is the sole general partner of Versant Venture Capital
V (Canada) LP. Neither Versant Ventures V, LLC nor any other entity under its
control, other than (i) Versant Venture Capital V, L.P., (ii) Versant
Affiliates Fund V, L.P., (iii) Versant Ophthalmic Affiliates Fund I, L.P. and
(iv) Versant Venture Capital V (Canada) LP, holds any shares or financial
instruments in the Company.

In Turku, December 14, 2015

Biotie Therapies Corp.

Timo Veromaa
President and CEO

For further information, please contact:

Virve Nurmi, Investor Relations Manager, Biotie Therapies Corp.
tel. +358 2 274 8900, e-mail: virve.nurmi@biotie.com

DISTRIBUTION:

NASDAQ OMX Helsinki Ltd
Main Media
www.biotie.com

---------------------------------------

This announcement is distributed by NASDAQ OMX Corporate Solutions on behalf of NASDAQ OMX Corporate Solutions clients.
The issuer of this announcement warrants that they are solely responsible for the content, accuracy and originality of the information contained therein.
Source: Biotie Therapies Oyj via Globenewswire

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