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MorphoSys AG: MorphoSys to Present Clinical Trial Data on Proprietary Programs at Upcoming ASCO Annual Meeting 2016

MorphoSys AG / MorphoSys to Present Clinical Trial Data on Proprietary
Programs at UpcomingASCO Annual Meeting 2016 . Processed and transmitted by
NASDAQ OMX Corporate Solutions.The issuer is solely responsible for the
content of this announcement.
MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX; OTC: MPSYY) today
announced the publication of three abstracts which were accepted for the 2016
American Society of Clinical Oncology (ASCO) Annual Meeting, taking place
from June 3 to June 7 in Chicago, Illinois, USA. The abstracts include
updated clinical data on the Company's proprietary drug candidate MOR202 from
a phase 1/2a study in patients with multiple myeloma as well as a patient
subgroup analysis from the phase 2 study of MOR208 in non-Hodgkin's lymphoma
(NHL). The MOR202 abstract has also been selected by the conference
organizers for discussion in a separate session. In addition, partners of
MorphoSys will present data on several HuCAL antibodies that are currently in
clinical development.

"We are delighted to publish a new package of clinical data at the preeminent
conference on clinical oncology. The data set provides additional insight
into the progress of our lead cancer compounds MOR208 and MOR202," commented
Dr. Arndt Schottelius, Chief Development Officer of MorphoSys AG. "For
MOR202, we are in particular looking forward to presenting additional
efficacy data from the dose escalation Phase 1/2a study in multiple myeloma
in combination with lenalidomide and with pomalidomide."

List of abstracts relating to MorphoSys's proprietary programs

Abstract #8012

MOR202 alone and in combination with pomalidomide or lenalidomide in relapsed
or refractory multiple myeloma: Data from clinically relevant cohorts from a
phase 1/2a study.
The poster presentation will include safety results and, in particular,
efficacy from additional patient cohorts receiving the anti CD38 antibody
MOR202 alone and in combination with pomalidomide or lenalidomide from the
ongoing trial. The poster presentation will take place on Monday, June 6,
8:00 am - 11:30 am CDT, as part of the Hematologic Malignancies - Plasma Cell
Dyscrasia track. The findings will be discussed at the poster discussion
session on Monday, June 6, 2016, 3:00 PM - 4:15 PM CDT, at E354b.

Abstract #7545

Subgroup analyses of diffuse large B-cell lymphoma (DLBCL) and indolent
lymphoma cohorts from a phase 2a study of single-agent MOR208 in patients
with relapsed or refractory non-Hodgkin's lymphoma (R-R NHL).
The poster presentation will include a subgroup analysis of an open-label,
multicenter, phase 2a study of the anti-CD19 antibody MOR208 in R-R NHL
patients progressing after at least one prior rituximab-containing therapy,
as described in the abstract. The poster presentation will take place on June
6, 8:00 am - 11:30 am CDT, as part of the Hematologic Malignancies - Lymphoma
and Chronic Lymphocytic Leukemia track.

Abstract #TPS7572

A phase 2 study of MOR208 plus idelalisib in patients with relapsed or
refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma
(SLL) previously treated with a Bruton's tyrosine kinase inhibitor
The poster presentation will include the trial design of an intended phase 2
study (COSMOS), which was originally planned to evaluate MOR208 in
combination with idelalisib in CLL and SLL, in particular
ibrutinib-refractory CLL, as described in the abstract. After the
discontinuation of several combination trials of idelalisib with other
compounds and clinical holds by the regulatory authorities in Europe and the
U.S., this planned trial is currently under review and discussions with
regulatory authorities are ongoing. The poster presentation will take place
on June 6, 8:00 am - 11:30 am CDT, as part of the Hematologic Malignancies -
Lymphoma and Chronic Lymphocytic Leukemia track.

List of abstracts for programs from MorphoSys's partnered discovery business

Additionally, MorphoSys's partners will present data for several HuCAL
antibodies, which are currently in clinical development:

Abstract #TPS8576

A pivotal randomized phase 2 study of anetumab ravtansine or vinorelbine in
patients with advanced or metastatic pleural mesothelioma after progression
on platinum/pemetrexed-based chemotherapy (NCT02610140).

Abstract #8564

Updated results of phase 1b study of tarextumab (TRXT, anti-Notch2/3) in
combination with etoposide and platinum (EP) in patients (pts) with untreated
extensive-stage small-cell lung cancer (ED-SCLC).

Abstract #530

Phase 1b/2 trial of BI 836845, an insulin-like growth factor (IGF)
ligand-neutralizing antibody, combined with exemestane (Ex) and everolimus
(Ev) in hormone receptor-positive (HR+) locally advanced or metastatic breast
cancer (BC): primary phase 1b results.

Abstract #3002

Phase 1b study of PF-05082566 in combination with pembrolizumab in patients
with advanced solid tumors.

Abstract #2516

Phase 1b study of WNT inhibitor vantictumab (VAN, human monoclonal antibody)
with Paclitaxel (P) in patients (pts) with 1st- to 3rd-line metastatic
HER2-negative breast cancer (BC).

Abstract #2509

Phase I study of anti-mesothelin antibody drug conjugate anetumab ravtansine

The full abstracts can be accessed online at

About MorphoSys:
MorphoSys developed HuCAL, the most successful antibody library technology in
the pharmaceutical industry. By successfully applying this and other patented
technologies, MorphoSys has become a leader in the field of therapeutic
antibodies, one of the fastest-growing drug classes in human healthcare.
Together with its pharmaceutical partners, MorphoSys has built a
therapeuticpipelineof more than 100 human antibody drug candidates for the
treatment of cancer, rheumatoid arthritis, and Alzheimer's disease, to name
just a few. With its ongoing commitment to new antibody technology and drug
development, MorphoSys is focused on making the healthcare products of
tomorrow. MorphoSys is listed on the Frankfurt Stock Exchange under the
symbol MOR. For regular updates about MorphoSys,

HuCAL®, HuCAL GOLD®, HuCAL PLATINUM®, CysDisplay®, RapMAT®, arYla®, Ylanthia®,
100 billion high potentials®, Slonomics®, Lanthio Pharma® and LanthioPep® are
registered trademarks of the MorphoSys Group.

This communication contains certain forward-looking statements concerning the
MorphoSys group of companies, The forward-looking statements contained herein
represent the judgment of MorphoSys as of the date of this release and
involve risks and uncertainties, Should actual conditions differ from the
Company's assumptions, actual results and actions may differ from those
anticipated, MorphoSys does not intend to update any of these forward-looking
statements as far as the wording of the relevant press release is concerned.

For more information, please contact:

MorphoSys AG
Dr. Claudia Gutjahr-Löser
Head of Corporate Communications&IR

Alexandra Goller
Senior Manager Corporate Communications&IR

Jochen Orlowski
Associate Director Corporate Communications&IR

Tel: +49 (0) 89 / 899 27-404

Media Release (PDF)


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The issuer of this announcement warrants that they are solely responsible for the content, accuracy and originality of the information contained therein.
Source: MorphoSys AG via Globenewswire


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