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2014-06-10

RaySearch Laboratories: First PBS / IMPT proton treatments with RayStation

Provision Center for Proton Therapy treats first patients in Tennessee
with the RayStation® treatment planning system from RaySearch
Laboratories AB.

On May 27, 2014 the first patient was treated with the Pencil Beam
Scanning (PBS) treatment technique at the Provision Center for Proton
Therapy in Knoxville, Tennessee, the state's first and only proton
therapy treatment facility. The clinical patient treatment plans were
created entirely on RayStation®, RaySearch's highly advanced
treatment planning and dose tracking software platform and delivered
on the IBA proton system.

PBS is the most sophisticated delivery technique in proton therapy. It
enables Intensity Modulated Proton Therapy (IMPT) that allows
clinicians to target a cancerous tumor by controlling both the
intensity and the spatial distribution with millimeter precision.
Earlier this year, the first patients were treated using the Uniform
Scanning technique at Provision.

The proton center opened less than two years after breaking ground in
April 2012. A 220-ton cyclotron, a particle accelerator that produces
protons, was installed a year ago in January 2013 at the center,
which sits on the 120-acre comprehensive outpatient medical campus at
Dowell Springs in Knoxville. In close collaboration with RaySearch,
Provision was able to get the treatment planning network installed,
have data collected and modeled, perform extensive quality assurance
and train their entire staff in only four months. "We knew this was
an aggressive timeline, but we were very confident in the
technologies that we had selected, and also in the people that were
focused on the project. Providing this region with proton therapy as
an option for cancer treatment is a vision that our organization has
tirelessly pursued. We are pleased with results and happy with our
selection of RaySearch as our partner," said Niek Schreuder, the VP
and Chief of Medical Physics for the center.

"The Provision Center for Proton Therapy is a model for what can be
achieved when people from multiple organizations come together and
work towards a common goal. Niek and his team brought a lot of
knowledge and expertise to the table and implemented a cutting edge
program safely and efficiently," says Marc Mlyn, President of
RaySearch Americas, Inc. "We are pleased that this was the first site
in the USA that implemented RayStation® clinically for proton therapy
- both for Uniform Scanning and PBS."

"Provision has a culture for excellent patient care and takes pride in
being at the forefront of leading-edge technologies," said Marcio
Fagundes, M.D., board-certified radiation oncologist and Medical
Director at the Provision Center for Proton Therapy. "The Provision
Center for Proton Therapy is an example of such commitment. Provision
selected RayStation® with the expectation that it would improve
efficiency and provide excellence in patient planning. RayStation®
has not only achieved these expectations but has changed the
landscape of all planning environments currently in practice."

"Proton therapy is a prioritized area for us and we have worked very
hard to create the leading solution for proton treatment planning
with support for all treatment modalities. It is of course a
historical event for us that RayStation® has now been implemented
clinically for proton therapy using the PBS treatment technique
meaning that the system is used to create the most advanced cancer
radiation treatments available", says Johan Löf, CEO of RaySearch.

The current version of RayStation® that has FDA clearance supports all
relevant proton treatment techniques such as Uniform Scanning, Double
Scattering and PBS / IMPT.

About Provision Center for Proton Therapy
Provision Center for Proton Therapy is the first cancer treatment
center of its kind in Tennessee and only the second in the
Southeastern United States. Open to all credentialed physicians and
health systems in the region, the Provision Center for Proton Therapy
will have three treatment rooms and will be able to treat up to 900
cancer patients annually, and will bring in many patients from
outside the area. Treatments will typically require daily 30 - 45
minute sessions for two months. The next closest location offering
proton therapy is 350 miles away. The center brings to Knoxville an
advanced cancer treatment capability that presently is available in
only a handful of cities. It is one of only 14 in the nation and 46
in the world.

About RayStation®
RayStation® integrates all RaySearch's advanced treatment planning
solutions into a flexible treatment planning system. It combines
unique features such as multi-criteria optimization tools with full
support for 4D adaptive radiation therapy. It also includes
functionality such as RaySearch's market-leading algorithms for IMRT
and VMAT optimization and highly accurate dose engines for photon,
electron and proton therapy. The system is built on the latest
software architecture and has a graphical user interface offering
state-of-the-art usability.

About RaySearch
RaySearch Laboratories is a medical technology company that develops
advanced software solutions for improved radiation therapy of cancer.
RaySearch provides the RayStation® treatment planning system to
clinics all over the world. In addition, RaySearch's products are
distributed through licensing agreements with leading partners such
as Philips, Nucletron, IBA, Varian and Brainlab. To date, 15 products
have been launched via partners and RaySearch's software is used by
over 2,500 clinics in more than 65 countries. RaySearch was founded
in 2000 as a spin-off from the Karolinska Institute in Stockholm and
the company is listed in the Small Cap segment on NASDAQ OMX
Stockholm.

For more information about RaySearch, visit www.raysearchlabs.com

For further information, please contact:
Johan Löf, President and CEO, RaySearch Laboratories AB
Telephone: +46 (0)8-545 061 30
johan.lof@raysearchlabs.com

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http://news.cision.com/raysearch-laboratories/r/first-pbs---impt-proton-...
http://mb.cision.com/Main/1102/9599132/254773.pdf

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